What is Fibrolamellar?

 

Primary liver cancer = cancer that originates/begins in the liver
Secondary liver cancer = cancer originated somewhere else but has spread to the liver
Liver resection surgery =  when part of the liver is removed
Hepatocellular Carcinoma = liver cancer, fibrolamellar is a subtype of liver cancer

 

Fibrolamellar is a variant of hepatocellular carcinoma that usually occurs in young patients between ages 20 to 40. The fibrolamellar variant of hepatocellular carcinoma differs from the "classical" form of hepatocellular carcinoma in several important aspects including:

  • Most patients with fibrolamellar hepatocellular carcinoma do not have underlying cirrhosis of the liver.
  • Hepatitis B infection is very uncommon in patients with fibrolamellar hepatocellular carcinoma.
  • The serum levels of alpha-fetoprotein are usually not elevated in patients with fibrolamellar hepatocellular carcinoma. 
     
     (below: CT scan of fibrolamellar tumor)                                                  



Fibrolamellar carcinoma has also been called eosinophilic hepatocellular carcinoma with lamellar fibrosis,
polygonal cell hepatocellular carcinoma with fibrous stroma, hepatocellular carcinoma with increased stromal fibrosis, eosinophilic glassy cell hepatoma,and fibrolamellar oncocytic hepatoma in various medical texts. 

Fibrolamellar affects males and females equally

Risk factors for fibrolamellar remain unidentified
                                                                                                                             

Currently surgery is the most effective means of treating and controlling fibrolamellar
(to the right: fibrolamellar cells under a microscope)


-Read more about fibrolamellar by clicking below.  Images and data courtesy of:

www.medifocushealth.com/OC031/Treatment-Options-for-Liver-Cancer_Fibrolamellar-Hepatocellular-Carcinoma.php
 

-What does the liver do and more about liver cancer from the American Cancer Society:

www.cancer.org/docroot/CRI/content/CRI_2_4_1X_What_is_liver_cancer_25.asp


-Click below to view the fibrolamellar Wikipedia entry:

en.wikipedia.org/wiki/Fibrolamellar_hepatocellular_carcinoma




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